ApoA-l Mimetic Peptide 4F Reduces Age-Related Lipid Deposition in Murine Bruch’s Membrane and Causes Its Structural Remodeling. (October 2017) Martin Rudolf, Armin Mir Mohi Sefata, Yoko Miuraa, Aysegül Tura, Walter Raasch, Mahdy Ranjbar, Salvatore Grisanti, Zouhair Aherrahrou, Anna Wagner, Jeffrey D. Messingee, David Garber, GM Anantharamaiah, and Christine A. Curcio. Department of Ophthalmology, University of Lübeck, Germany; […]
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Myc proto-oncogenes regulate diverse cellular processes during development, but their roles during morphogenesis of specific tissues are not fully understood. This study found that c-myc regulates cell proliferation in mouse lens development and previous genome-wide studies suggested functional roles for N-myc in developing lens. The role of N-myc was examined in mouse lens development. Genetic […]
Read MoreThe vitreous humor of the eye is a clear gel-like structure comprised of collagen and water and fills the back of the eye.
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Michael D. Flood; Johnnie M. Moore-Dotson; and Erika D. Eggers, University of Arizona. This study was conducted with IRRF support — Erika D. Eggers. (Published August 15, 2018) In this study, it was determined how dopamine D1 receptors in the inner retina contribute to this modulation. It was found that D1 receptor activation significantly decreased […]
On Earth, it takes LambdaVision approximately five days for each of its three robotic stations to produce an implant. The process involves a series of alternating dipping steps, which are subject to the effects of gravity. Once complete, the process results in a membrane approximately 60 um (micrometers) thick. A micrometer is one-millionth of a meter.
Read MoreA manuscript summarizing the results of Dr. Seddon’s study was published in Investigative Ophthalmology & Visual Science, (IOVS): Investigative Ophthalmology & Visual Science Optical Coherence Tomography Features Preceding the Onset of Advanced Age-Related Macular Degeneration Investigative Ophthalmology & Visual Science (IOVS), Optical Coherence Tomography Features Preceding the Onset of Advanced Age-Related Macular Degeneration, Daniela Ferrara, […]
Project Title: Retinal Imaging with Optical Coherence Tomography in Neonatal Brain Injury to Evaluate and Improve Visual and Neurologic Outcomes. Sally Ong, MD, the 2017 Loris and David Rich Postdoctoral Scholar, was born and raised in Batu Pahat, a small town in Malaysia, and attended Duke University in Durham, North Carolina, on a full scholarship […]
Journal of Cellular Biochemistry: Critical role of endoplasmic reticulum stress in chronic endothelial activation – induced visual deficits in tie2-tumor necrosis factor mice. (October 2018: Volume 119, Issue 10) Dr. Lenin is a graduate of the University of Madras, India, where she received her PhD in Biochemistry and Molecular Biology Ophthalmology before coming to the […]
2019 marked the fifth year of collaboration between the International Retinal Research Foundation (IRRF) and Research to Prevent Blindness (RPB) in which our collective resources were used to support focused research into the causes and possible cures for age-related macular degeneration (AMD). The American Macular Degeneration Foundation (AMDF) joined RPB and IRRF in establishing four more catalyst awards in 2019. These Catalyst Awards for Innovative Research Approaches for AMD will provide up to $300,000 per award, payable over 3 years.
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