The role of microglia-mediated inflammation on the cell fate of proliferating Müller glia following p27Kip1 inactivation and outer retina degeneration in aged mice
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Marco Bassetto, PhD University of California Irvine, USA PROJECT TITLE: Pharmacological treatment for maculopathies based on oral administration of new visual cycle modulator Dr. Bassetto developed his PhD in the field of ocular drug delivery. His early research aimed at establishing methods to enhance permeation of therapeutics within the eye after non-invasive, topical application. Most […]
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Zhiquan Liu, PhD Stanford University, USA PROJECT TITLE: Gene therapy for PDE6A deficient retinitis pigmentosa via CRISPR base editing Dr. Liu earned his undergraduate and graduate training in biology at Jilin University in China, was in the top 1% of students and published many high impact papers. He went on to earn his PhD degree […]
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In 2023, 13 grant applications across the spectrum of basic, translational and clinical science were received for consideration for funding by the Research and Education Fund and Grant Awards program. All were carefully reviewed by a committee consisting of Jason Hsu, Nora Lad, Eric Nudleman, Susanna Park, Yannis Paulus, Charles Wycoff and David Zacks. The 2023 […]
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RESEARCH PROJECT TITLE: Mechanobiology of Choroidal Vascular Loss in Early Age-related Macular Degeneration Kaustabh Ghosh, PhD Associate Professor of Ophthalmology David Geffen School of Medicine, UCLA Doheny Eye Institute Dr. Ghosh will study how the blood vessels in the outer retina (choroidal vessels) degenerate early on in age-related macular degeneration (AMD). Dr. Ghosh recently discovered […]
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PROJECT TITLE: Aberration in myeloid-derived pro-angiogenic cells in type-2 diabetes mellitus; implication for diabetic retinopathy? Mahnaz Shariatzadeh1, Trishka R.R. Binda1, Conny van Holten-Neelen2, Josianne C. ten Berge2, Jose P. Martinez Ciriano4, King T. Wong4, Willem A. Dik2 and Pieter J.M. Leenen2 1Department of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands. 2Department of Immunology, Erasmus University […]
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PROJECT TITLE: Ubiquitylation of BBSome is required for ciliary assembly and signaling. Francesco Chiuso, Rossella delle Donne, Giuliana Giamundo, Laura Rinaldi, Domenica Borzacchiello, Federica Moraca, Daniela Intartaglia, Rosa Iannuci, Emanuela Senatore, Luca Lignitto, Carrodo Garbi, Paolo Conflitti, Bruno Catalanotti, Ivan Conte, & Antonio Feliciello ABSTRACT: Bardet-Biedl syndrome (BBS) is a ciliopathy characterized by retinal degeneration, […]
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Funding Partnerships that Provide Opportunities to Young Investigators: Suva Roy, PhD, from Duke University, School of Medicine, Durham, North Carolina, received the 2023 Ramon Dacheux II Memorial Travel Grant. This award has allowed him to attend the annual meeting of the Association for Research in Vision and Ophthalmology (ARVO) held in New Orleans, Louisiana. The […]
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Thomas Wubben, MD, PhD University of Medicine, Medical School, Kellogg Eye Center Project Title: Elucidating the Role of Glutamine Catabolism in Cone Photoreceptor Metabolic Homeostasis and Survival Dr. Wubben’s research focuses on the intersection of retinal metabolism and vitreoretinal disease. Understanding the metabolic pathways that support retinal cell function and survival and how these pathways […]
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