Pathogenic neovascularization in diabetic retinopathy and age-related macular degeneration: the role of monocyte-derived pro-angiogenic cells

Project Title:  Pathogenic neovascularization in diabetic retinopathy and age-related macular degeneration: the role of monocyte-derived pro-angiogenic cells Willem Dik, PhD Erasmus Medical Center Department of Immunology Rotterdam, The Netherlands $103,500 for one year Dr. Dik’s research focuses on identification of cellular and molecular mechanisms underlying (chronic) inflammatory processes and related tissue and organ dysfunction, with […]

Read More

Role of photoreceptors in local inflammation and pathological angiogenesis in diabetic retinopathy

Project Title:  Role of photoreceptors in local inflammation and pathological angiogenesis in diabetic retinopathy Irina De la Huerta, MD, PhD Department of Ophthalmology and Visual Sciences Vanderbilt Eye Institute, Vanderbilt University Nashville, Tennessee USA $100,000 for one year Dr. De la Huerta obtained her undergraduate degree magna cum laude from Harvard University.  Following her medical […]

Read More
Headshot of Cagri Besirli, MD, PhD

PKM2 metabolic reprogramming to prevent photoreceptor death in a preclinical model of macular degeneration

Project Title:  PKM2 metabolic reprogramming to prevent photoreceptor death in a preclinical model of macular degeneration. Cagri G. Besirli, MD, PhD Assistant Professor, Ophthalmology and Visual Sciences University of Michigan, Ann Arbor, Michigan USA $100,000 for one year Dr. Besirli’s area of practice is gene therapy for inherited retinal diseases.  Other areas include disease and […]

Read More
Headshot of Rodrigo Martins, PhD

Smc1 and the Cohesin Complex in Retinal Development and Disease

PROJECT TITLE: Smc1 and the Cohesin Complex in Retinal Development and Disease: A New Mouse Model of Photoreceptor Degeneration ABSTRACT: Myc proto-oncogenes regulate diverse cellular processes during development, but their roles during morphogenesis of specific tissues are not fully understood.  This study found that c-myc regulates cell proliferation in  mouse lens development and previous genome-wide […]

Read More