Current Eye Research

ApoA-l Mimetic Peptide 4F Reduces Age-Related Lipid Deposition in Murine Bruch’s Membrane and Causes Its Structural Remodeling. (October 2017) Martin Rudolf, Armin Mir Mohi Sefata, Yoko Miuraa, Aysegül Tura, Walter Raasch, Mahdy Ranjbar, Salvatore Grisanti, Zouhair Aherrahrou, Anna Wagner, Jeffrey D. Messingee, David Garber, GM Anantharamaiah, and Christine A. Curcio. Department of Ophthalmology, University of Lübeck, Germany; […]

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N-myc regulates growth and fiber cell differentiation in lens development

Myc proto-oncogenes regulate diverse cellular processes during development, but their roles during morphogenesis of specific tissues are not fully understood. This study found that c-myc regulates cell proliferation in mouse lens development and previous genome-wide studies suggested functional roles for N-myc in developing lens. The role of N-myc was examined in mouse lens development. Genetic […]

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Dopamine D1 receptor activation contributes to light-adapted changes in retinal inhibition to rod bipolar cells

Michael D. Flood; Johnnie M. Moore-Dotson; and Erika D. Eggers, University of Arizona. This study was conducted with IRRF support — Erika D. Eggers. (Published August 15, 2018) In this study, it was determined how dopamine D1 receptors in the inner retina contribute to this modulation. It was found that D1 receptor activation significantly decreased […]

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Astrocyte structural reactivity and plasticity in models of retinal detachment

Photo Above: Drs. Geoffrey Lewis and Steven Fisher and Gabriel Luna, BA, Research Specialist with the Neuroscience Research Institute. Experimental Eye Research, Astrocyte structural reactivity and plasticity in models of retinal detachment, Gabriel Luna, Patrick W. Keeley, Benjamin E. Reese, Kenneth A Linberg, Geoffrey P. Lewis, Steven K. Fisher.  Neuroscience Research Institute, University of California, […]

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Synthesis and Biological Evaluation of Novel Homoisoflavonoids for Retinal Neovascularization

Photo Above: The Corson Lab Group. Timothy Corson front right. Journal of Medicinal Chemistry.  “Synthesis and Biological Evaluation of Novel Homoisoflavonoids for Retinal Neovascularization,”  Helesha D. Basavarajappa, Bit Lee, Hyungjun Lee, Rania S. Sulaiman, Hongchan An, Carlos Magaña, Mehdi Shadmand, Alexandra Vayl, Gangaraju Rajashekhar, Eun-Yeong Kim, Young-Ger Suh, Kiho Lee, Seung-Yong Seo, and Timothy W. […]

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