In 2024, the IRRF pledged $1.5 million to establish the Teresa and Michael A. Callahan, MD Endowed Chair in Ophthalmology and Visual Sciences at UAB. This prestigious gift will advance vision research, support global collaboration, and honor Dr. Callahan’s legacy in ophthalmic surgery and education.
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The complement factor H (CFH) Y402H polymorphism (rs1061170) imparts the strongest risk for age-related macular degeneration (AMD), the leading cause of blindness in the elderly.
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ApoA-l Mimetic Peptide 4F Reduces Age-Related Lipid Deposition in Murine Bruch’s Membrane and Causes Its Structural Remodeling. (October 2017) Martin Rudolf, Armin Mir Mohi Sefata, Yoko Miuraa, Aysegül Tura, Walter Raasch, Mahdy Ranjbar, Salvatore Grisanti, Zouhair Aherrahrou, Anna Wagner, Jeffrey D. Messingee, David Garber, GM Anantharamaiah, and Christine A. Curcio. Department of Ophthalmology, University of Lübeck, Germany; […]
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Myc proto-oncogenes regulate diverse cellular processes during development, but their roles during morphogenesis of specific tissues are not fully understood. This study found that c-myc regulates cell proliferation in mouse lens development and previous genome-wide studies suggested functional roles for N-myc in developing lens. The role of N-myc was examined in mouse lens development. Genetic […]
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Michael D. Flood; Johnnie M. Moore-Dotson; and Erika D. Eggers, University of Arizona. This study was conducted with IRRF support — Erika D. Eggers. (Published August 15, 2018) In this study, it was determined how dopamine D1 receptors in the inner retina contribute to this modulation. It was found that D1 receptor activation significantly decreased […]
Project Title: Retinal Imaging with Optical Coherence Tomography in Neonatal Brain Injury to Evaluate and Improve Visual and Neurologic Outcomes. Sally Ong, MD, the 2017 Loris and David Rich Postdoctoral Scholar, was born and raised in Batu Pahat, a small town in Malaysia, and attended Duke University in Durham, North Carolina, on a full scholarship […]
Journal of Cellular Biochemistry: Critical role of endoplasmic reticulum stress in chronic endothelial activation – induced visual deficits in tie2-tumor necrosis factor mice. (October 2018: Volume 119, Issue 10) Dr. Lenin is a graduate of the University of Madras, India, where she received her PhD in Biochemistry and Molecular Biology Ophthalmology before coming to the […]
CIB2 in the retina: cell types, function and molecular mechanism Saumil S. Sethna, PhD University of Maryland School of Medicine Baltimore, Maryland Dr. Sethna joined the lab of Zubair M. Ahmed, PhD, in the Department of Otolaryngology – Head & Neck Surgery at the University of Maryland in March 2015, working as a research fellow. […]
Cholesterol Homeostasis in Age-related Macular Degeneration (AMD). Norimitsu Ban, MD Washington University Department of Ophthalmology St. Louis, Missouri Dr. Ban received his M.D. degree from Keio University School of Medicine, Tokyo, Japan in 2005. He then joined the graduate program at the prestigious Keio University Graduate School of Medicine, Tokyo, and completed his PhD in […]
Photo Above: The Corson Lab Group. Timothy Corson front right. Journal of Medicinal Chemistry. “Synthesis and Biological Evaluation of Novel Homoisoflavonoids for Retinal Neovascularization,” Helesha D. Basavarajappa, Bit Lee, Hyungjun Lee, Rania S. Sulaiman, Hongchan An, Carlos Magaña, Mehdi Shadmand, Alexandra Vayl, Gangaraju Rajashekhar, Eun-Yeong Kim, Young-Ger Suh, Kiho Lee, Seung-Yong Seo, and Timothy W. […]