Cover image of Journal of the American Chemical Society J. Am. Chem. Soc. 2026, 148, 21, 21846-21857

Light-Activated RPE65 Inhibitors Enable On-Demand Visual Cycle Control

(Journal of the American Chemical Society) J. Am. Chem. Soc. 2026, 148, 21, 21846-21857 Marco Bassetto, Bowen Li, Xiuyuan Chen, Jianyu Zhang, Yulun Hu, Jordan Zaluski, Lauren M. Brumit, Preston M Willis, Felix Grun, Krysztof Palczewski, Philia D Kiser, and Gregory P Tochtrop ABSTRACT Light initiates visual perception, but it also exacerbates a subset of […]

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Photo of Marco Bassetto, PhD

2023 Charles D. Kelman, MD Postdoctoral Scholar

Marco Bassetto, PhD University of California Irvine, USA PROJECT TITLE: Pharmacological treatment for maculopathies based on oral administration of new visual cycle modulator Dr. Bassetto developed his PhD in the field of ocular drug delivery. His early research aimed at establishing methods to enhance permeation of therapeutics within the eye after non-invasive, topical application. Most […]

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Photo of Shintaro Shirahama, MD, PhD

2022 Alston Callahan, MD Postdoctoral Scholar

Shintaro Shirahama, MD, PhD Schepens Eye Research Institute Harvard Medical School PROJECT TITLE: Development of a novel transplant-independent therapy for retinal pigment epithelium (RPE) dysfunction using epigenetic reprogramming of RPE stem cells Dr. Shirahama has a strong background in ocular inflammatory diseases, including infectious and non-infectious uveitis. After graduating from medical school in Japan, Dr. […]

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Photo of So Goto, MD, PhD

2022 Loris and David Rich Postdoctoral Scholar

So Goto, MD, PhD University of California Berkeley School of Optometry So Goto, MD, PhD, has been selected as the 2022 Loris and David Rich Postdoctoral Scholar for his project, Role of retinal pigment epithelium in choroidal thickness modulation and myopia maculopathy. After receiving a Bachelor of Medicine (MD) from Kanazawa University School of Medicine […]

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