Project Title: Retinal Vasculopathy with Cerebral Leukoencephalopathy and Systemic Manifestations (RVCL-S), a Vascular Eye Model.
- Gisela Terwindt, MD, PhD
- Leiden University Medical Center, The Netherlands
- $100,000 for one year
Dr. Terwindt is an Associate Professor of Neurology at Leiden University Medical Center, whose special interest is headache and cerebral hereditary angiopathies (CHA). She diagnoses more than 1500 new headache patients a year and aims to combine scientific and clinical work. She introduced a semi-automated questionnaire system (LUMINA and LUCA), and is currently developing other interface tools.
Dr. Terwindt’s IRRF-supported study intends to identify retinal imaging markers of disease progression in participants with and without the mutation leading to RVCL, a rare monogenetic microvasculopathy that affects the retina, the brain and other organs. The proposal builds on her world expertise on this condition, first identified by her group.