Thomas Wubben, MD, PhD
Assistant Professor, Ophthalmology & Visual Science
University of Michigan
Project Title: Photoreceptor Protection Via Metabolic Targeting of the Integrated Stress Response
Understanding the metabolic underpinnings that orchestrate stress pathway activation in photoreceptors is critical to creating innovative, therapeutic strategies for retinal degenerative diseases. This proposal will identify the link between metabolic dysregulation and stress pathway activation to potentially provide novel, gene-agnostic, photoreceptor neuroprotective strategies with immediately translatable applications.
